Psilocybin Therapy & Personality Structure

Psilocybin Therapy & Personality Structure Major depression is an illness that frequently affects people and is linked to significant morbidity, socioeconomic hardship, and rates of successful suicide (1, 2). The World Health Organization (WHO) has rated it as the fourth largest contributor to the world burden of disease (5), with a prediction that it will […]
Treatment of Anxiety and Other Psychological Distress Associated With Terminal Illnesses with MDMA-Assisted Psychotherapy

Treatment of Anxiety and Other Psychological Distress Associated With Terminal Illnesses with MDMA-Assisted Psychotherapy The triumph of modern medicine has led to an increase in the number of people with life-threatening illnesses (LTI), many of whom also suffer from existential anguish, sadness, and anxiety. We explore a unique strategy for treating anxiety in LTI patients […]
Ketamine-Assisted Therapy for Substance-Use Disorders

Ketamine-Assisted Therapy for Substance-Use Disorders A dissociative anaesthetic, ketamine primarily affects the central nervous system by antagonistically binding to the n-methyl-d-aspartate (NMDA) receptor. Ketamine has recently gained popularity as a fast-acting anti-depressant, but other studies have shown that it is also effective for lowering problematic alcohol and drug usage. The preclinical and clinical evidence on […]
Psychedelic Neuroscience

Psychedelic Neuroscience This article discusses the neurobiological effects of psychedelic substances, the alterations in brain activity that ensue, and the incorporation of conventional ideas. As any scientist who has experienced it is aware, science is still in the early stages of comprehending psychedelic chemical mechanisms and considerably further from understanding the psychedelic state. Introduction: The […]
The Psychopathology of Trauma: Psilocybin and MDMA

The Psychopathology of Trauma: Psilocybin and MDMA This article looks at similar psycho-neurobiological alterations and how trauma affects psychiatric morbidity. Post-Traumatic Stress Disorder (PTSD) requires trauma, but trauma history is strongly connected with a number of psychiatric disorders. According to some data, Major Depressive Disorder (MDD) is the psychiatric disorder that develops most frequently after […]
MD-MA: Novel Perspectives

MD-MA: Novel Perspectives The tiny, amphetamine-like chemical known as MDMA commonly referred to in its unregulated form as “E” or “ecstasy” in Europe and as “molly” in the USA has had a reputation that has gone from being touted as a potential new therapeutic tool to being stigmatized as a brain-damaging recreational drug. Most of […]
Serotonergic Drugs and Creativeness

Serotonergic Drugs and Creativeness Over time, it has been shown that psychedelics have inspired the creativity of musicians, painters, and scientists since they help to heighten and speed up their creative processes. This has led a lot of people to turn to magic mushrooms in order to enhance their cognitive abilities. Human Creativity Since the […]
Psilocybin’s Long-Term Reduction of OCD Symptoms

Psilocybin’s Long-Term Reduction of OCD Symptoms Obsessive-compulsive disorder (OCD) is a neuro-psychiatric ailment that is extremely common and incapacitating, for which the currently available treatments are insufficiently effective and alternative therapies deserve top emphasis. Psilocybin may offer those suffering from this ailment a secure and efficient therapeutic option. This chapter provides a brief overview of […]
Cannabidiol (CBD): Latest Uses in the Treatment of Neurological Disorders

Cannabidiol (CBD): Latest Uses in the Treatment of Neurological Disorders Cannabidiol (CBD), a non-psychoactive and pharmacologically significant component of cannabis, exhibits a number of advantageous properties. Anti-oxidative, anti-inflammatory, and neuro-protective properties have been discovered. The recent resurgence of mainly unproven and uncontrolled cannabis-based preparations on medical therapies may have its largest impact in the field […]
Cannabis-based Medications as Therapies for Adult Patients Suffering from Chronic Neuropathic Pain

Cannabis-based Medications as Therapies for Adult Patients Suffering from Chronic Neuropathic Pain The emphasis of this paper is an innovative approach to treating and managing persistent neuropathic pain. Only a small percentage of persons receive significant relief from current pharmacological treatments (medication) for neuropathic pain, and they frequently have side effects that outweigh the advantages. […]
MDMA Therapy for Alcohol Use Disorder: Novel Perspectives

MDMA Therapy for Alcohol Use Disorder: Novel Perspectives Alcohol consumption disorder causes substantial clinical, social, and personal hardship for those who have it, as well as a sizable financial burden on society. After medical detoxification and focused treatment programs, there is a high rate of relapse with current treatments, both psychological and pharmaceutical. Lysergic acid […]
Psilocybin’s Migraine-Suppressing Effects: An Exploratory Controlled Study

Psilocybin’s Migraine-Suppressing Effects: An Exploratory Controlled Study Controlled studies are sparse, although anecdotal data suggest that certain 5-hydroxytryptamine 2A receptor ligands, such as psilocybin, may have long-lasting therapeutic effects after low doses in headache disorders. According to this experimental article, psilocybin has a long-lasting therapeutic impact on migraine headache after just one dose. An interesting […]
Suicidal Ideation (SI) Reduction in Treatment-Resistant Depression: Single and Repeated Ketamine Infusion (TRD)

Suicidal Ideation (SI) Reduction in Treatment-Resistant Depression: Single and Repeated Ketamine Infusion (TRD) Subanesthetic intravenous ketamine infusions given repeatedly may prolong the fast reduction in suicidal ideation (SI) brought on by a single infusion. The goal of this secondary analysis was to compare the SI decrease caused by a single ketamine infusion to an active […]
Psychopharmacology: MDMA Therapy for Alcohol-Use Disorder

Alcohol consumption disorder places a heavy clinical, social, and personal cost on those who experience it, as well as a huge financial impact on society. After medical detoxification and focused treatment programmes, there is a high rate of relapse with current treatments, both psychological and pharmaceutical. Lysergic acid diethylamide (LSD)-assisted psychotherapy, used to treat what […]
Do Magic Mushrooms Affect Your Productivity & Focus?

Magic mushrooms are often misunderstood, and many countries have made it illegal to even possess them. However, there’s several studies and tons of anecdotal evidence that shrooms can have intense effects on your brain, including benefits like changes to your productivity and focus. You can take large doses of magic mushrooms, which will cause you […]