Brain Atrophy & Psychedelics Among the primary causes of impairment are stroke and traumatic brain injury (TBI). Nearly half of individuals with severe TBI who need hospitalization still have significant…

Psilocybin Therapy & Personality Structure Major depression is an illness that frequently affects people and is linked to significant morbidity, socioeconomic hardship, and rates of successful suicide (1, 2). The…

Treatment of Anxiety and Other Psychological Distress Associated With Terminal Illnesses with MDMA-Assisted Psychotherapy The triumph of modern medicine has led to an increase in the number of people with…

Ketamine-Assisted Therapy for Substance-Use Disorders A dissociative anaesthetic, ketamine primarily affects the central nervous system by antagonistically binding to the n-methyl-d-aspartate (NMDA) receptor. Ketamine has recently gained popularity as a…

Psychedelic Neuroscience This article discusses the neurobiological effects of psychedelic substances, the alterations in brain activity that ensue, and the incorporation of conventional ideas. As any scientist who has experienced…

The Psychopathology of Trauma: Psilocybin and MDMA This article looks at similar psycho-neurobiological alterations and how trauma affects psychiatric morbidity. Post-Traumatic Stress Disorder (PTSD) requires trauma, but trauma history is…

MD-MA: Novel Perspectives The tiny, amphetamine-like chemical known as MDMA commonly referred to in its unregulated form as "E" or "ecstasy" in Europe and as "molly" in the USA has…

Serotonergic Drugs and Creativeness Over time, it has been shown that psychedelics have inspired the creativity of musicians, painters, and scientists since they help to heighten and speed up their…

Psilocybin's Long-Term Reduction of OCD Symptoms Obsessive-compulsive disorder (OCD) is a neuro-psychiatric ailment that is extremely common and incapacitating, for which the currently available treatments are insufficiently effective and alternative…

Cannabidiol (CBD): Latest Uses in the Treatment of Neurological Disorders Cannabidiol (CBD), a non-psychoactive and pharmacologically significant component of cannabis, exhibits a number of advantageous properties. Anti-oxidative, anti-inflammatory, and neuro-protective…

Cannabis-based Medications as Therapies for Adult Patients Suffering from Chronic Neuropathic Pain The emphasis of this paper is an innovative approach to treating and managing persistent neuropathic pain. Only a…

MDMA Therapy for Alcohol Use Disorder: Novel Perspectives Alcohol consumption disorder causes substantial clinical, social, and personal hardship for those who have it, as well as a sizable financial burden…

Psilocybin's Migraine-Suppressing Effects: An Exploratory Controlled Study Controlled studies are sparse, although anecdotal data suggest that certain 5-hydroxytryptamine 2A receptor ligands, such as psilocybin, may have long-lasting therapeutic effects after…

Suicidal Ideation (SI) Reduction in Treatment-Resistant Depression: Single and Repeated Ketamine Infusion (TRD) Subanesthetic intravenous ketamine infusions given repeatedly may prolong the fast reduction in suicidal ideation (SI) brought on…

5. Implementing MDMA Therapy It is critical to emphasize that there is still disagreement among scientists regarding the pharmacology of MDMA when talking about its methods of action. The known…